|
11. Squalene epoxide is then converted to lanosterol by lanosterol synthase. |
|
Biosynthesis of Cholesterol: |
|
CoA |
|
O |
|
O |
|
S |
|
H2O |
|
CoA |
|
CoA |
|
O |
|
S |
|
+ |
|
Acetyl-CoA |
|
Acetoacetyl-CoA |
|
1. Condensation of Acetyl-CoA and Acetoacetyl-CoA, catalyzed by HMG-CoA synthase, forms HMG-CoA (3-hydroxy-3-methylglutaryl-CoA). |
|
1. |